Hooo boy this probably won't be a pretty game between two teams that are anything but elite.
I like Jacoby Brissett and think the Colts offense will gel at some point (probably when they had some more pieces to it...) but the Broncos defense is/should be far better than the Colts defense so while neither team will be able to score much on offense (Broncos offense is typically ANEMIC), I think the Broncos D will show up in primetime tonight.
I'm picking the Broncos to win this, but I don't think they have a huge edge here.